| Date | Time | Opponent | Rank | Site | TV | Result | Attendance | Source |
|---|
| 7:00 p.m. | Chowan* | | | | W 42–0 | 3,014 | [1] |
| September 16 | 6:00 p.m. | Eastern Kentucky* | | - Bob Waters Field at E. J. Whitmire Stadium
- Cullowhee, NC
| | W 20–17 | 8,247 | [2] |
| September 23 | 7:00 p.m. | at No. 3 Furman | No. 22 | | CSS | L 7–42 | 14,232 | [3] |
| September 30 | 6:00 p.m. | No. 25 Georgia Southern | No. 24 | - Bob Waters Field at E. J. Whitmire Stadium
- Cullowhee, NC
| | L 14–24 | 10,483 | [4] |
| October 7 | 2:00 p.m. | at Elon | | | | L 19–37 | 4,374 | [5] |
| October 14 | 3:30 p.m. | Chattanooga | | - Bob Waters Field at E. J. Whitmire Stadium
- Cullowhee, NC
| | L 14–17 OT | 8,540 | [6] |
| October 21 | 2:00 p.m. | at The Citadel | | | | L 27–30 OT | 15,495 | [7] |
| October 28 | 1:30 p.m. | at Wofford | | | | L 7–35 | 7,072 | [8] |
| November 4 | 1:00 p.m. | at Liberty* | | | | L 0–21 | 8,286 | [9] |
| November 11 | 4:00 p.m. | No. 1 Appalachian State | | | | L 9–31 | 13,742 | [10] |
| November 18 | 12:00 p.m. | at No. 3 (FBS) Florida* | | | PPV | L 0–62 | 90,233 | [11] |
|
[12]
- ↑ "WCU chews up Chowan". Asheville Citizen-Times. September 1, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "Catamounts top Colonels". Messenger-Inquirer. September 17, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "Felton runs over Cats". Asheville Citizen-Times. September 24, 2006. Retrieved September 24, 2022 – via Newspapers.com.
- ↑ "Eagles prevail over Cats". Asheville Citizen-Times. October 1, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "New and improved Phoenix wins". News and Record. October 8, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "Lopez duo helps Chattanooga top Western Carolina". News and Record. October 15, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "The Citadel edges Catamounts in OT". Sun-News. October 22, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "Terriers run past Western Carolina". Asheville Citizen-Times. October 29, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "No doubt about it: LU triumphs". The News and Advance. November 5, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "App State downs Western". Hickory Daily Record. November 12, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "Gators crush Catamounts". Pensacola News Journal. November 19, 2006. Retrieved July 13, 2025 – via Newspapers.com.
- ↑ "2021 Western Carolina Catamount Football Media Guide" (PDF). Cullowhee, North Carolina: Western Carolina University Athletics. 2021. p. 123. Retrieved November 22, 2021.