Aleksandra Wodnar-Filipowicz | |
|---|---|
 Aleksandra Wodnar-Filipowicz (2025) | |
| Alma mater | Institute of Biochemistry and Biophysics at the Polish Academy of Sciences, Warsaw |
Aleksandra Wodnar-Filipowicz is a Swiss-Polish biologist and professor specializing in experimental hematology. She was a faculty member at the University of Basel in Switzerland, where she was Professor of Experimental Haematology in the Department of Biomedicine.[1] She was involved in teaching and research at the Department of Biomedicine[2] and the Basel Stem Cell Network.[3] She coordinated educational workshops and seminars on stem cell biology and was actively involved in mentoring students and young scientists.
Early Life and Education
editAleksandra Wodnar-Filipowicz began her scientific career in Poland, where she was affiliated with the Institute of Biochemistry and Biophysics at the Polish Academy of Sciences in Warsaw [4]. Her early research focused on molecular biology, particularly the structure and function of messenger RNA.[5]
Research Focus
editWodnar-Filipowicz has made contributions to the study of hematopoietic stem cells Reference!, investigating their biological properties and therapeutic potential Reference!. Her research has focused on the molecular mechanisms that regulate hematopoiesis and the immune system, including the role of growth factors such as the Flt3 ligand Reference!. She has also pioneered the development of natural killer (NK)[6] cell-based immunotherapies for leukemia, with an emphasis on selectively targeting leukemic stem cells while sparing healthy hematopoietic cells. In addition to her research, she has contributed to scientific education by coordinating workshops and seminars for the Basel Stem Cell Network, supporting the advancement of stem cell research and training in Switzerland.[7]
Research Focus Alternative
editWodnar-Filipowicz has contributed to research on hematopoietic stem and progenitor cells, particularly their regulation by cytokines and their role in immune system development.[8] Her work has examined molecular mechanisms of hematopoiesis, including the function of growth factors such as the Flt3 ligand.[8] She has also co-authored studies on the development and function of natural killer (NK) cells derived from hematopoietic progenitor cells.[9] In addition, her research has addressed the characterization of hematopoietic progenitor cell populations and their differentiation in vitro.[10]
Selected Publications
edit- Wodnar-Filipowicz, A. (2003). Flt3 ligand: role in control of hematopoietic and immune functions of the bone marrow. News in Physiological Sciences, 18, 247–251. https://doi.org/10.1152/nips.01452.2003
- Wodnar-Filipowicz, A. (2003). Flt3 ligand: role in control of hematopoietic and immune functions of the bone marrow. News in Physiological Sciences, 18, 247–251. https://doi.org/10.1152/nips.01452.2003
- Wodnar-Filipowicz, A., Szczesna, E., Zan-Kowalczewska, M., Muthukrishnan, S., Szybiak, U., Legocki, A. B., & Filipowicz, W. (1978). 5′‐Terminal 7‐Methylguanosine and mRNA Function. European Journal of Biochemistry, 92(1), 69–80. https://doi.org/10.1111/j.1432-1033.1978.tb12724.x
References
edit- ↑ "Researchgate Aleksandra Wodnar-Filipowicz". researchgate.net. Retrieved 2025-07-14.
- ↑ "Emeriti Professors". unibas.ch. Retrieved 2025-08-12.
- ↑ "Basel Stem Cell Network". baselstemcells.ch. Retrieved 2025-08-12.
- ↑ "ETranslation of potato virus x RNA into high molecular weight proteins". wiley.com. Retrieved 2026-04-29.
- ↑ "5'-Terminal 7-Methylguanosine and mRNA Function". wiley.com. Retrieved 2026-04-29.
- ↑ Langenkamp, Ulrich; Siegler, Uwe; Jörger, Aleksandra; Diermayr, Stefan; Gratwohl, Alois; Kalberer, Christian P; Wodnar-Filipowicz (2009-11-01). "Human acute myeloid leukemia CD34+CD38− stem cells are susceptible to allorecognition and lysis by single KIR-expressing natural killer cells". haematologica. 94 (1q): e5. doi:10.3324/haematol.2009.005967.
- ↑ "Course directory". unibas.ch. Retrieved 2025-08-12.
- 1 2 Wodnar-Filipowicz, Aleksandra (2003). "Flt3 ligand: role in control of hematopoietic and immune functions". Cytokine & Growth Factor Reviews. 14 (5): 427–438. doi:10.1016/S1359-6101(03)00049-2. PMID 14563335.
- ↑ Lotzová, E.; Wodnar-Filipowicz A. (2003). "Natural killer cell development and function in hematopoietic stem cell transplantation". Leukemia & Lymphoma. 44 (8): 1239–1246. doi:10.1080/1042819031000103913.
- ↑ Wodnar-Filipowicz, Aleksandra; others (1998). "Expression of hematopoietic growth factor receptors on human cord blood CD34+ cells". Blood. 91: 2701–2709.