The entire route was only in Allegheny County.[1] However, on November 6, 2009, it was extended into Beaver, Lawrence, and Mercer counties.

Location Mile
[citation needed]
# Destinations Notes
Old New
Rosslyn Farms

US 22 west / US 30 west Pittsburgh International Airport
Continuation beyond I-79
0.51 1A 64A I-79 Erie, Washington
0.82 1B 64B Rosslyn Farms Westbound exit and eastbound entrance
Carnegie 1.33 West Busway Eastbound exit and westbound entrance; buses only
1.73 2 65 PA 50 Carnegie, Heidelberg
Green Tree 3.49 4A 67 PA 121 Mount Lebanon, Green Tree, Crafton
Pittsburgh 4.18 4B 68 Parkway Center Drive Westbound exit and eastbound entrance
4.86 5A 69A
US 19 south (Banksville Road)
West end of US 19/US 19 Truck overlap; eastbound exit is via exit 69C
5.10 5B 69B


US 19 Truck south / PA 51 south Uniontown
Westbound exit is via exit 69A
5.18 5C 69C

US 19 north / PA 51 north West End
East end of US 19 overlap; eastbound exit and westbound entrance
5.80 Fort Pitt Tunnel under Mount Washington
6.07 5C 69C
PA 837 (West Carson Street) to PA 51 West End
Westbound exit and eastbound entrance
6.19 Fort Pitt Bridge over the Monongahela River
6.24 6B 70A Boulevard of the Allies, Liberty Avenue Mellon Arena Eastbound exit and westbound entrance
6C 70B Fort Duquesne Boulevard, Strip District Eastbound exit and westbound entrance
1A 70C


I-279 north / US 19 Truck north Fort Duquesne Bridge, North Shore
1B 70D Stanwix Street No exit number eastbound (from I-279 south only); originally exit 1[2]
1C 71A Grant Street
1D 71B Second Avenue Westbound exit only
2A 72A Forbes Avenue Oakland Eastbound exit and westbound entrance
2B 72B


To I-579 / PA 885 north / Boulevard of the Allies Liberty Bridge
Westbound exit and eastbound entrance
3 72 PA 885 Oakland, Glenwood Westbound exit and eastbound entrance; signed as exits 3A (south) and 3B (north)
5 74 Squirrel Hill, Homestead (Blue Belt)
Edgewood 7 77 Edgewood, Swissvale
Wilkinsburg 8A 78A
US 30 east Forest Hills
East end of US 30 overlap; no westbound exit
8B 78B
PA 8 north Wilkinsburg
9 79A Greensburg Pike Eastbound exit and westbound entrance
Churchill 10A 79B PA 130 Churchill
10B 80

US 22 Bus. east Monroeville
Eastbound exit and westbound entrance
Penn Hills 11 81
PA 791 north (Yellow Belt) Penn Hills
Monroeville 14A 84A
PA 48 south (Orange Belt) Monroeville
Eastbound exit and westbound entrance
14B 84B Plum (Orange Belt) Eastbound exit and westbound entrance
16

US 22 Bus. west Monroeville
Westbound exit and eastbound entrance
17[2]
US 22 east Murrysville
15 85 I-76 / Penna Turnpike Eastbound exit and westbound entrance

Exit list with PA 60 Expansion

edit
County Location Mile # Destinations Notes
PA-60 I-376 [1]
Allegheny County Robinson Township 9.4 1B
US 22 east/ US 30 east - Pittsburgh
To I-79.
9.4 1A 60A
US 22 west/ US 30 west/ Orange Belt CCW - Weirton, WV
Orange Belt joins northbound and leaves southbound.
North Fayette Township 9.7 1 59 Robinson Town Centre Boulevard
Moon Township 10.9 2 58 Montour Run Road
11.7 3 57
PA 60 BUS/Orange Belt CCW - Moon, Cargo-Service
Orange Belt joins southbound and leaves northbound. Access to Robert Morris University and Air Force Reserve Base.
Findlay Township 13.0 4 56 McClaren Road Access to Pennsylvania Air National Guard and the town of Imperial.
16.1 6 53 Pittsburgh International Airport - Main Terminals and Parking Area

PA 576 east to US 22 - Weirton
17.0 7 52
To US 30 - Clinton
19.0 8 51 w, 50 e
PA 60 BUS (Flaugherty Run Rd) - Moon
Cargo-service.
Beaver Hopewell Township 21.4 9 48 PA 151 - Hopewell
24.6 10 45 Aliquippa
Center Township 27.7 11 42 Center Township Access To Community College of Beaver County.
30.0 12 39 PA 18 - Monaca, Shippingport Beaver Valley Mall, Penn State University Beaver Campus, and Bruce Mansfield Nuclear Power Plant.
Vanport Township 31.1 13 38 PA 68 - Beaver, Midland
Brighton 33.3 14 36 Brighton
Chippewa Township 38.1 15/29 31 PA 51 - Chippewa
Southern toll barrier. End/Begin Turnpike 60

CASH CUSTOMERS: $0.65 toll for two-axle vehicles.

E-ZPASS CUSTOMERS: $0.63 toll for two-axle vehicles.

Big Beaver 40.3 31 (old 16) 29
PA 551 To PA 18 - Beaver Falls
CASH CUSTOMERS: $0.65 toll for two-axle vehicles entering northbound and exiting southbound.

E-ZPASS CUSTOMERS: $0.63 toll for two-axle vehicles entering northbound and exiting southbound.

43.5 33 (old 17) 26 I-76/Pa Tpk/PA 351 - Ohio, Harrisburg - Ellwood City, New Galilee, Koppel.
Lawrence North Beaver Township 49.2 40 (old 18) 20
PA 168/PA 18 - Moravia
CASH CUSTOMERS: $0.65 toll for two-axle vehicles entering southbound and exiting northbound.

E-ZPASS CUSTOMERS: $0.63 toll for two-axle vehicles entering southbound and exiting northbound.

Northern toll barrier.

CASH AND E-ZPASS CUSTOMERS: $1.25 toll for two-axle vehicles.

52.9 43 (old 19) 17 PA 108 - Mount Jackson CASH CUSTOMERS: $0.65 toll for two-axle vehicles entering northbound and exiting southbound.

E-ZPASS CUSTOMERS: $0.63 toll for two-axle vehicles entering northbound and exiting southbound.

Union Township End/Begin Turnpike 60
54.4 45/20 15
US 422 - Butler
Southern terminus of US 422/ PA 60 concurrency.
55.9 13 US 224 - Poland, Ohio, downtown New Castle
Northern terminus of US 422/ PA 60 concurrency.
57.1 E-W 12
US 422 west/US 422 BUS (Sampson St) - Youngstown, OH
Neshannock Township 59.9 24 9
PA 18 (Mitchell Rd)
Pulaski Township 64.3 25 5 PA 208 - New Wilmington, Pulaski Access to Westminster College.
Mercer Shenango Township 67.5 2 PA 18 (Sharon Rd)
68.9 1C PA 318 - West Middlesex Southbound only.
69.3 1B/A I-80 - Mercer, Youngstown, OH Gordon Ward Interchange. Western terminus.