Trimazosin

Trimazosin
Clinical data
ATC code	C02CA03 (WHO) ;
Identifiers
	IUPAC name (2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate;
CAS Number	35795-16-5 ; HCl: 53746-46-6 ;
PubChem CID	37264;
ChemSpider	34203 ;
UNII	31L760807H; HCl: 827T79ILE7 ;
KEGG	D08212 ;
ChEMBL	ChEMBL513301 ;
CompTox Dashboard (EPA)	DTXSID50189319 ;
ECHA InfoCard	100.047.924
Chemical and physical data
Formula	C20H29N5O6
Molar mass	435.481 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3;
	InChI InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) ; Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N ;
	(what is this?) (verify)

Trimazosin is a sympatholytic alpha-1 blocker.^[1]^[2]

References

↑ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. doi:10.1007/BF00870988. PMID 3780829. S2CID 19123951.
↑ U.S. patent 3,669,968

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Clinical data

ATC code	C02CA03 (WHO)
Identifiers
IUPAC name (2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate
CAS Number	35795-16-5^Y HCl: 53746-46-6^Y
PubChem CID	37264
ChemSpider	34203^N
UNII	31L760807H HCl: 827T79ILE7^Y
KEGG	D08212^N
ChEMBL	ChEMBL513301^N
CompTox Dashboard (EPA)	DTXSID50189319
ECHA InfoCard	100.047.924
Chemical and physical data
Formula	C₂₀H₂₉N₅O₆
Molar mass	435.481 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3
InChI InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23)^N Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N^N
^NY (what is this?) (verify)