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Template:Potencies and durations of natural estrogens by intramuscular injection

Potencies and durations of natural estrogens by intramuscular injection
EstrogenFormDose (mg)Duration by dose (mg)Refs
EPDCICD
EstradiolAq. soln.?–<1 d[1]
Oil soln.40–60–1–2 ≈ 1–2 d[2][3]
Aq. susp.?3.50.5–2 ≈ 2–7 d; 3.5 ≈ >5 d[2][4][5][6][7]
Microsph.?–1 ≈ 30 d[8][9]
Estradiol benzoateOil soln.25–35–1.66 ≈ 2–3 d; 5 ≈ 3–6 d[10][11]
Aq. susp.20–10 ≈ 16–21 d[12][13][14]
Emulsion?–10 ≈ 14–21 d[14][15]
Estradiol dipropionateOil soln.25–30–5 ≈ 5–8 d[10]
Estradiol valerateOil soln.20–3055 ≈ 7–8 d; 10 ≈ 10–14 d;
40 ≈ 14–21 d; 100 ≈ 21–28 d		[11][16]
Estradiol benz. butyrateOil soln.?1010 ≈ 21 d[17][18]
Estradiol cypionateOil soln.20–30–5 ≈ 11–14 d[11]
Aq. susp.?55 ≈ 14–24 d[19][20][21]
Estradiol enanthateOil soln.?5–1010 ≈ 20–30 d[22][23][24]
Estradiol dienanthateOil soln.?–7.5 ≈ >40 d[25][26]
Estradiol undecylateOil soln.?–10–20 ≈ 40–60 d;
25–50 ≈ 60–120 d		[27][28]
Polyestradiol phosphateAq. soln.40–60–40 ≈ 30 d; 80 ≈ 60 d;
160 ≈ 120 d		[29][30]
EstroneOil soln.?–1–2 ≈ 2–3 d[3][31]
Aq. susp.?–0.1–2 ≈ 2–7 d[32]
EstriolOil soln.?–1–2 ≈ 1–4 d[3][33]
Polyestriol phosphateAq. soln.?–50 ≈ 30 d; 80 ≈ 60 d
Notes and sources
Notes: All aqueous suspensions are of microcrystalline particle size. Estradiol production during the menstrual cycle is 30–640 µg/d (6.4–8.6 mg total per month or cycle). The vaginal epithelium maturation dosage of estradiol benzoate or estradiol valerate has been reported as 5 to 7 mg/week. An effective ovulation-inhibiting dose of estradiol undecylate is 20–30 mg/month. Sources: Main/General: [34][35][36][37][38][39][40][41][42] Miscellaneous: [43][44][45]
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