Talk:Cyclin-dependent kinase

Latest comment: 4 months ago by ThatTrainGuy1945 in topic Mitotic trigger waves

Cyclin and Cdk used in Cell Cycle

edit

Consider adding the Phase associated with a cyclin-Cdk complex:

Phase Cyclin Cdk
G1 D, E CDK4, CDK2
S A CDK2
M B CDK1

Rage italic 17:19, 5 February 2007 (UTC)Reply

Actually, this isn't entirely correct: Cdk1 is sufficient to drive the mammalian cell cycle. 157.193.141.24 (talk) 14:13, 23 November 2007 (UTC)Reply

Cell division kinase

edit

I just heard somebody say "... CDKs, or cell division kinases ...". Are they talking crap / getting confused with the cdcs, or is it an acceptable term? I had only ever heard it expanded to Cyclin-dependent kinase before now, but there an awful lot of Google results for this other one. Joe D (t) 10:29, 28 April 2007 (UTC)Reply

Proposed shift of content from Medical significance

edit

The Medical significance section overlaps CDK inhibitor so propose that most of the section here be merged into that article with a summary left here. - Rod57 (talk) 23:29, 10 February 2017 (UTC)Reply

Likely AI-generated edits

edit

Hi - I added the AI generated tag here because the additions by Fatma Abukhater, such as this, display many strong indicators of LLM use and thus need review for accuracy, source-to-text integrity, and the like. Gnomingstuff (talk) 15:54, 29 October 2025 (UTC)Reply

I just rewrote the lead, removed the "evolutionary history" section (which spent two paragraphs saying nothing), and replaced Table 1 with the previous version. But could we possibly just revert all Fatma Abukhater's edits (and possibly block them from editing this page)?
This is an incredibly important subject, covered in all cell biology courses and medical basic science sequences. To see someone who clearly doesn't know what they're doing come in and take an LLM sledgehammer to the whole thing is beyond infuriating; I would argue it's disruptive editing. WP:CIR and all that. I'm going to bookmark this page and add it to my list of critical science articles rendered incomprehensible by AI. I will work on it as I get the time over the next couple of weeks, but in the meantime I'll see if we can get a revert and possibly a topic ban. WeirdNAnnoyed (talk) 13:57, 2 November 2025 (UTC)Reply
I finished cleaning up the article. I ended up removing some potentially useful content, such as the historical aspects of CDK research, but overall the sources have now been verified and the suffocating "crucial aspect...highlighting the critical role of...not only opportunities but also challenges" text has been removed. I think a few of the sources could be improved and some content added back by a PERSON with knowledge of the field. I now have concerns about the figure that I moved to the therapeutics section, which is copied straight out from this paper: . I may pull this figure as a COPYVIO. AI template removed. WeirdNAnnoyed (talk) 13:45, 30 November 2025 (UTC)Reply
Never mind, looks like the user who added it was the copyright holder. Although I've never published in a journal that let me retain the copyright to any figures in the paper...WeirdNAnnoyed (talk) 13:48, 30 November 2025 (UTC)Reply

Mitotic trigger waves

edit

Hello, Rather than ask a million and one people who have edited this page, I decided to place this here for present and future visitors. I was wondering if anyone knew a possible for this current article to link to mitotic trigger waves. I know very little about this kind of biology, so... Cheers, ThatTrainGuy1945 (talk) 22:21, 31 January 2026 (UTC)Reply