Wikipedia

List of opioids

This is a list of opioids, opioid antagonists and inverse agonists.

Opium poppy (Papaver somniferum) flower

Opium and poppy straw derivatives

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Seedhead of opium poppy with white latex

Crude opiate extracts whole opium products

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Natural opiates

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Semisynthetics including Bentley compounds

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Morphine family

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Structures of Morphine family
Morphine family
Chemical structure of 14-hydroxymorphine.14-Hydroxymorphine Chemical structure of 2,4-dinitrophenylmorphine.2,4-Dinitrophenylmorphine Chemical structure of 6-methyldihydromorphine.6-Methyldihydromorphine Chemical structure of 6-methylenedihydrodesoxymorphine.6-Methylenedihydrodesoxymorphine Chemical structure of 6-acetyldihydromorphine.6-Acetyldihydromorphine
Chemical structure of azidomorphine. Azidomorphine Chemical structure of chlornaltrexamine. Chlornaltrexamine Chemical structure of chloroxymorphamine. Chloroxymorphamine Chemical structure of desomorphine.Desomorphine
(Dihydrodesoxymorphine)		 Chemical structure of dihydromorphine. Dihydromorphine
Chemical structure of ethyldihydromorphine. Ethyldihydromorphine Chemical structure of hydromorphinol. Hydromorphinol Chemical structure of methyldesorphine. Methyldesorphine Chemical structure of N-phenethylnormorphine. N-Phenethylnormorphine Chemical structure of 6-nicotinoyldihydromorphine.6-nicotinoyldihydromorphine
Chemical structure of RAM-378. RAM-378

3,6-diesters of morphine

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Codeine-dionine family

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Morphinones and morphols

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Structures
Morphinones and morphols
Chemical structure of 14-cinnamoyloxycodeinone. 14-Cinnamoyloxycodeinone Chemical structure of 14-ethoxymetopon. 14-Ethoxymetopon Chemical structure of 14-methoxymetopon. 14-Methoxymetopon Chemical structure of 14-phenylpropoxymetopon. 14-Phenylpropoxymetopon Chemical structure of 7-spiroindanyloxymorphone. 7-Spiroindanyloxymorphone
Chemical structure of 8,14-dihydroxydihydromorphinone. 8,14-Dihydroxydihydromorphinone Chemical structure of acetylcodone. Acetylcodone Chemical structure of acetylmorphone. Acetylmorphone Chemical structure of α-hydrocodol (dihydrocodeine). α-hydrocodol
(Dihydrocodeine)		 Image not available. Bromoisopropropyldihydromorphinone
Chemical structure of codeinone. Codeinone Chemical structure of codorphone. Codorphone Chemical structure of codeine phosphate. Codol
(Codeine Phosphate)		 Chemical structure of codoxime. Codoxime Chemical structure of IBNtxA. IBNtxA
Chemical structure of thebacon. Thebacon Chemical structure of hydrocodone. Hydrocodone Chemical structure of hydromorphone. Hydromorphone Chemical structure of hydroxycodeine. Hydroxycodeine Chemical structure of metopon.Metopon
(methyldihydromorphinone)
Chemical structure of morphenol. Morphenol Chemical structure of morphinone. Morphinone Chemical structure of morphol. Morphol Chemical structure of N-phenethyl-14-ethoxymetopon. N-Phenethyl-14-ethoxymetopon Chemical structure of oxycodone. Oxycodone
Chemical structure of oxymorphol. Oxymorphol Chemical structure of oxymorphone. Oxymorphone Chemical structure of pentamorphone. Pentamorphone Chemical structure of semorphone. Semorphone

Morphides

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Dihydrocodeine series

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Nitrogen morphine derivatives

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Hydrazones

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Structures
Hydrazones
Chemical structure of oxymorphazone. Oxymorphazone

Halogenated morphine derivatives

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Active opiate metabolites

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Morphinans

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Levomethorphan

Morphinan series

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Others

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Benzomorphans

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Structures
Benzomorphans
Chemical structure of 5,9 alpha-diethyl-2-hydroxybenzomorphan.5,9 alpha-diethyl-2-hydroxybenzomorphan
(5,9-DEHB)		 Chemical structure of 8-Carboxamidocyclazocine. 8-Carboxamidocyclazocine General structure of alazocine. Alazocine Chemical structure of anazocine. Anazocine Chemical structure of bremazocine. Bremazocine
Chemical structure of butinazocine. Butinazocine Chemical structure of carbazocine. Carbazocine Chemical structure of cogazocine. Cogazocine Chemical structure of cyclazocine. Cyclazocine Chemical structure of dezocine. Dezocine
Chemical structure of eptazocine. Eptazocine Chemical structure of etazocine. Etazocine Chemical structure of ethylketocyclazocine. Ethylketocyclazocine Chemical structure of fedotozine. Fedotozine Chemical structure of fluorophen. Fluorophen
Chemical structure of gemazocine. Gemazocine Chemical structure of ibazocine. Ibazocine Chemical structure of ketazocine. Ketazocine Chemical structure of metazocine. Metazocine Chemical structure of moxazocine . Moxazocine
Chemical structure of pentazocine. Pentazocine Chemical structure of phenazocine. Phenazocine Chemical structure of quadazocine. Quadazocine Chemical structure of tonazocine. Tonazocine
Chemical structure of volazocine. Volazocine Chemical structure of zenazocine. Zenazocine

4-Phenylpiperidines

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Pethidine

Pethidines (meperidines)

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Structures
Pethidines (meperidines)
Chemical structure of 4-fluoropethidine.4-Fluoropethidine Chemical structure of 8-carboxamidocyclazocine. 8-Carboxamidocyclazocine General structure of allylnorpethidine. Allylnorpethidine Chemical structure of anileridine. Anileridine Chemical structure of benzethidine. Benzethidine
Chemical structure of carperidine. Carperidine Chemical structure of difenoxin. Difenoxin Chemical structure of diphenoxylate. Diphenoxylate Chemical structure of etoxeridine. Etoxeridine Chemical structure of furethidine. Furethidine
Chemical structure of hydroxypethidine. Hydroxypethidine Chemical structure of morpheridine. Morpheridine Chemical structure of meperidine-N-oxide. Meperidine-N-oxide Chemical structure of oxpheneridine. Oxpheneridine Chemical structure of pethidine. Pethidine
Chemical structure of pethidine intermediate A. Pethidine intermediate A Chemical structure of pethidine intermediate B. Pethidine intermediate B Chemical structure of pethidine intermediate C. Pethidine intermediate C Chemical structure of pheneridine. Pheneridine Chemical structure of phenoperidine. Phenoperidine
Chemical structure of piminodine. Piminodine Chemical structure of properidine.Properidine Chemical structure of sameridine. Sameridine

Prodines

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Ketobemidones

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Others

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Open chain opioids

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Methadone

Amidones

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Methadols

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Moramides

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Thiambutenes

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Phenalkoxams

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Ampromides

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Others

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Anilidopiperidines

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Fentanyl
Structures
Anilidopiperidines
Chemical structure of 3-allylfentanyl.3-Allylfentanyl Chemical structure of 3-methylfentanyl.3-Methylfentanyl Chemical structure of 3-methylthiofentanyl.3-Methylthiofentanyl Chemical structure of 4-phenylfentanyl .4-Phenylfentanyl Chemical structure of alfentanil. Alfentanil
Chemical structure of alphamethylacetylfentanyl. Alphamethylacetylfentanyl Chemical structure of alphamethylfentanyl. Alphamethylfentanyl Chemical structure of alphamethylthiofentanyl. Alpha-methylthiofentanyl Chemical structure of benzylfentanyl. Benzylfentanyl Chemical structure of betahydroxyfentanyl. Betahydroxyfentanyl
Chemical structure of betahydroxythiofentanyl. Betahydroxythiofentanyl Chemical structure of betamethylfentanyl. Betamethylfentanyl Chemical structure of brifentanil. Brifentanil Chemical structure of carfentanil. Carfentanil Chemical structure of fentanyl. Fentanyl
Chemical structure of lofentanil. Lofentanil Chemical structure of mirfentanil. Mirfentanil Chemical structure of ocfentanil. Ocfentanil Chemical structure of ohmefentanyl. Ohmefentanyl Chemical structure of parafluorofentanyl. Parafluorofentanyl
Chemical structure of phenaridine. Phenaridine Chemical structure of remifentanil. Remifentanil Chemical structure of sufentanil. Sufentanil Chemical structure of thenylfentanyl. Thenylfentanyl Chemical structure of thiofentanyl. Thiofentanyl
Chemical structure of trefentanil. Trefentanil

Oripavine derivatives

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Phenazepanes

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Pirinitramides

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Structures
Pirinitramides
Chemical structure of bezitramide.

Bezitramide

 Chemical structure of piritramide.

Piritramide

Benzimidazoles

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Indoles

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Beta-Amino Ketones

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Diphenylmethylpiperazines

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Opioid peptides

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β-neoendorphin

Dynorphins

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Endomorphins

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Endorphins

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Enkephalins

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Propeptides

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Others / unknown

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Others

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Opioid antagonists and inverse agonists

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Biased ligands

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Receptor heteromer targeting ligands

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Uncategorized opioids

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Combination drug formulations containing opioids

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See also

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References

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  1. ↑ ChemIndex CAS Registry Number 3371-56-0
  2. ↑ ChemIndex CAS Registry Number 509-56-8
  3. ↑ ChemIndex CAS Registry Number 63715-94-6
  4. ↑ NCBI PubChem SID 750205
  5. ↑ chembase [permanent dead link] cbid_346222
  6. ↑ Gomes I, Fujita W, Gupta A, Saldanha SA, Saldanha AS, Negri A, Pinello CE, Eberhart C, Roberts E, Filizola M, Hodder P, Devi LA (2013). "Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity". Proc. Natl. Acad. Sci. U.S.A. 110 (29): 12072–7. Bibcode:2013PNAS..11012072G. doi:10.1073/pnas.1222044110. PMC 3718106. PMID 23818586.
  7. ↑ Yekkirala AS, Lunzer MM, McCurdy CR, Powers MD, Kalyuzhny AE, Roerig SC, Portoghese PS (2011). "N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers". Proc. Natl. Acad. Sci. U.S.A. 108 (12): 5098–103. Bibcode:2011PNAS..108.5098Y. doi:10.1073/pnas.1016277108. PMC 3064379. PMID 21385944.
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  • Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time." Russian Chemical Bulletin. August 2008, Volume 57, Issue 8, pp 1773–1774. Date: 11 Aug 2009; I. V. Evsikova, S. K. Moiseev, P. V. Petrovskii, V. N. Kalinin. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1739–1740
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