Lexington Medical, Inc. (founded in 2013) is an American medical device manufacturing company. The company is known for its innovative surgical stapling product, the AEON endoscopic stapler.[1][2]
History
editLexington Medical, Inc. was founded in 2013[3] by Leon Amariglio in Massachusetts. In 2017, it received U.S. FDA 510(k) clearance for the AEON Endoscopic Stapler, used in laparoscopic procedures.[4] In 2021, the product reached its 10,000-surgery milestone[5][6] and received FDA clearance for the AEON Endoscopic Powered Stapler in 2024.[7][8]
AEON surgical stapler
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AEON surgical staplers were introduced in 2018 by Lexington Medical.[1] The product is used to staple and cut tissue for resection, transection, and creation of anastomosis.[9][10][11] A trial evaluating the AEON Powered Stapling System was presented in the British Journal of Surgery in 2024. The study assessed device safety, firing mechanism performance, and initial clinical outcomes, contributing to the body of evidence supporting AEON's surgical utility.[12][2]
According to the journal Innovations in Surgery and Interventional Medicine (ISIM) published in 2025, the AEON endovascular stapler demonstrated improved outcomes, including a reduction in postoperative pancreatic fistula from 65% to 20% during distal pancreatectomy, along with enhanced staple-line hemostasis in comparison to Medtronic's Endo GIA device.[13]
References
edit- 1 2 Mickevicius, A. "IBC Oxford University Oral Abstract 42 - Interim results of prospective clinical trial: evaluation of the AEON endoscopic powered stapler handle and reload in primary sleeve gastrectomy". academic.oup.com. Oxford Academic. Retrieved 1 June 2026.
- 1 2 Sheen, Aali J.; Bandyopadhyay, Samik; Baltatzis, Minas; Deshpande, Rahul; Jamdar, Saurabh; Carino, Nicola de Liguori (2023-04-12). "Preliminary experience in laparoscopic distal pancreatectomy using the AEON™ endovascular stapler". Frontiers in Oncology. 13. ISSN 2234-943X. Retrieved 1 June 2026.
- ↑ "Lexington Medical, Inc. - Corporation Summary". Massachusetts Secretary of the Commonwealth. Retrieved 1 June 2026.
- ↑ "Premarket Notification 510(k) Summary - K171589". U.S. Food and Drug Administration. Retrieved 2025-07-02.
- ↑ Barbella, Michael (June 16, 2021). "Lexington Medical Reaches 10000 Surgery Milestone for its Endostapling Device". Medical Product Outsourcing. Retrieved November 25, 2025.
- ↑ "Lexington Medical Inc, United States Revenue". MedicalDevice-Network.com (GlobalData). June 16, 2021. Retrieved 1 June 2026.
- ↑ "Premarket Notification 510(k) Summary - K234039". U.S. Food and Drug Administration. Retrieved 1 June 2026.
- ↑ Kacik, Alex (June 28, 2024). "FDA clears 8 devices, including AI-driven surgical tools". Modern Healthcare. Retrieved 1 June 2026.
- ↑ Raftopoulos, Yannis; Rajkumar, Shruthi; Davidson, Elana; Papasavas, Pavlos (2022). "Prospective Randomized Comparison of Linear Endostaplers During Laparoscopic Sleeve Gastrectomy". Obesity Surgery. 32 (10): 3472–3480. doi:10.1007/s11695-022-06240-4. PMID 35974292.
- ↑ Sheen, Aali J.; Bandyopadhyay, Samik; Baltatzis, Minas; Deshpande, Rahul; Jamdar, Saurabh; de Liguori Carino, Nicola (2023). "Preliminary experience in laparoscopic distal pancreatectomy using the AEON endovascular stapler". Frontiers in Oncology. 13 1146646. doi:10.3389/fonc.2023.1146646. PMC 10130406. PMID 37124511.
- ↑ Redmann, James G.; Lavin, Thomas E.; French, Matthew S. (2020). "Improving Hemostasis in Sleeve Gastrectomy With Alternative Stapler". JSLS. 24 (4) e2020.00073. doi:10.4293/JSLS.2020.00073. PMC 7791089. PMID 33447003.
- ↑ "First-in-man experience using the AEON Powered Stapling System". British Journal of Surgery. 112 (Supplement_5): znaf036.042. 2024. Retrieved 2025-07-21.
- ↑ Sheen, Aali J.; Barrie, Jenifer; Stathakis, Panagiotis; Jamdar, Saurabh (March 2025). "Innovations in Hepatopancreatobiliary Surgery: A Review of LOTUS‑Bowa Liver Blade and AEON Endovascular Stapler". Innovations in Hepatopancreatobiliary Surgery. 5 (2025): 6–12. doi:10.36401/ISIM-24-02. Retrieved 2025-07-21.