Wikipedia

JoAnn Trejo

JoAnn Trejo is an American pharmacologist, cell biologist, and professor in the Department of Pharmacology, School of Medicine at University of California, San Diego.[1] She is also the senior assistant vice chancellor for Health Sciences Faculty Affairs.[2] Trejo studies cell signalling by protease-activated G protein-coupled receptors (GPCRs) in inflammation and cancer.[3][4][5][6]

JoAnn Trejo
Alma materUniversity of California, Davis University of California, San Diego
Employer(s)University of California, San Diego
Websitehttp://trejolab.ucsd.edu/Home.html/

Early Life and education

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Trejo was born in French Camp (January 23, 1964) and raised in Stockton in San Joaquin County, California.[7] She grew up the youngest of five children in a single-parent household of Mexican migrant farm workers.[8] Trejo graduated from Saint Mary's High School and obtained a bachelor's of science from the University of California, Davis in 1986.[9][10] She earned her PhD in Physiology and Pharmacology at University of California, San Diego in 1992 and an MBA from the Rady School of Management at University of California, San Diego in 2015.[9][10]

Career

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Trejo completed postdoctoral training with Professor Shaun Coughlin at the Cardiovascular Research Institute (CVRI), University of California, San Francisco.[9] In 2000, she joined the faculty as an assistant professor in the Department of Pharmacology at University of North Carolina, Chapel Hill.[9] She was recruited to University of California, San Diego as a tenured associate professor in the Department of Pharmacology in 2008 and was promoted to full professor in 2012.[11] In 2014, she was appointed vice chair of the Department of Pharmacology.[9] In 2015, she became the associate dean for Health Sciences Faculty Affairs and was appointed assistant vice chancellor in 2019 and senior assistant vice chancellor for Health Sciences Faculty Affairs in 2023.[12] Trejo is responsible for developing and implementing data-driven strategies, initiatives and programs for enhancing success, recruitment, and retention of faculty across Health Sciences at University of California, San Diego.[9][13]

Research interests

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Trejo studies the regulatory mechanisms that control signalling by protease-activated receptors, a family of G protein-coupled receptors (GPCRs) with critical functions in vascular inflammation and cancer. She has been continuously funded by the NIH since 2001 and has authored over a hundred peer-reviewed research papers.[3][4][5] She is known for her discoveries of mechanisms that govern activated GPCR biased signaling, endosomal signaling and signal regulation by the multi-functional beta- and alpha-arrestin adaptor proteins in the context of endothelial dysfunction and progression of triple-negative breast cancer.[14][15][16][17] She is associate editor for Molecular Biology of the Cell, serves on the editorial boards for the Journal of Biological Chemistry, Molecular Pharmacology, Current Opinion in Cell Biology, and PNAS Nexus. Trejo is engaged in an additional area of research that is focused on understanding factors that enhance success of early career faculty in academic medicine and science as well as postdoctoral fellow transition to the professoriate. [18][19][20]

Mentoring and training the next generation of scientists

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Trejo is a recognized leader in mentorship and in advancing the success of early career faculty and postdoctoral fellows.[9] She has trained over 100 postdocs, graduate students and undergraduate students in her laboratory. She is the director of the NIH-funded IRACDA program at University of California, San Diego, which has trained over 130 postdocs, of which 65% have transitioned to the professoriate as tenure-track faculty. Some work at R1 research intensive institutions.[9][21] She also leads NIH-funded research education programs that investigate the professional trajectories of early career faculty in academic medicine and science.[22][23] Trejo has assisted many early career faculty at University of California, San Diego, particularly in research development and grant writing. [24][25][26][27]

Awards

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JoAnn Trejo has received multiple awards for her research and mentoring. [9] [28]

References

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  1. ↑ https://profiles.ucsd.edu/joann.trejo
  2. ↑ https://vchs.ucsd.edu/about/leadership/trejo.html
  3. 1 2 "Some cancer therapies may avert cardiovascular disease". Medical News Today. 29 September 2018. Retrieved 2019-02-15.
  4. 1 2 "How cells repurpose their garbage disposal systems to promote inflammation: Study introduces potential new application for cancer drugs that inhibit a family of enzymes known as ubiquitin ligases". ScienceDaily. Retrieved 2019-02-15.
  5. 1 2 "What Makes Blood Vessels Leaky: New Insights for Sepsis Therapeutics". UC Health - UC San Diego. Retrieved 2021-10-19.
  6. ↑ https://today.ucsd.edu/story/how-one-receptor-can-help-or-hurt-your-blood-vessels
  7. ↑ https://www.nature.com/articles/d41586-025-02634-3
  8. 1 2 "JoAnn Trejo selected for 2020 ASCB Prize for Excellence in Inclusivity". www.newswise.com. Retrieved 2020-09-27.
  9. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 "JoAnn Trejo | UCSD Profiles". profiles.ucsd.edu. Retrieved 2019-02-15.
  10. 1 2 3 "UC San Diego's Joann Trejo to Be Honored with ASCB's EE Just Award | Newswise: News for Journalists". www.newswise.com. Retrieved 2019-02-15.
  11. ↑ https://pharmacology.ucsd.edu/faculty/department-faculty1/joann-trejo.html
  12. ↑ https://profiles.ucsd.edu/joann.trejo
  13. ↑ "Two UC San Diego Scientists Elected to National Academy of Medicine". UC Health - UC San Diego. Retrieved 2021-10-19.
  14. ↑ https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00119-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124726001191%3Fshowall%3Dtrue
  15. ↑ https://www.pnas.org/doi/full/10.1073/pnas.2106623118
  16. ↑ https://www.science.org/doi/abs/10.1126/scisignal.abc1044
  17. ↑ https://journals.biologists.com/jcs/article/134/8/jcs254888/237789/Arrestin-ARRDC3-tumor-suppressor-function-is?guestAccessKey=
  18. ↑ https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science/article/systemwide-health-sciences-faculty-mentor-training-program-is-associated-with-improved-effective-mentoring-and-institutional-climate/595963985DDCE5378C7D66A679C48EA3
  19. ↑ https://www.ingentaconnect.com/contentone/magna/jfd/2025/00000039/00000001/art00014
  20. ↑ https://academic.oup.com/academicmedicine/article/101/1/34/8418308?login=true
  21. ↑ "San Diego IRACDA". Retrieved 2021-10-19.
  22. ↑ "Not Just Checking a Box". ucsdnews.ucsd.edu. Retrieved 2021-10-19.
  23. ↑ "Faculty Development". medschool.ucsd.edu. Retrieved 2021-10-19.
  24. ↑ https://www.the-scientist.com/grant-writing-training-improves-funding-odds-for-faculty-73969
  25. ↑ https://today.ucsd.edu/story/uc-san-diego-health-sciences-grant-writing-course-helps-launch-successful-research-careers
  26. ↑ https://academic.oup.com/academicmedicine/article/101/1/34/8418308?login=true
  27. ↑ https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science/article/systemwide-health-sciences-faculty-mentor-training-program-is-associated-with-improved-effective-mentoring-and-institutional-climate/595963985DDCE5378C7D66A679C48EA3
  28. ↑ https://www.sandiegouniontribune.com/2018/06/07/san-diego-science-reaches-top-tier-in-new-global-survey/
  29. ↑ "2017 E.E. Just Award winner is JoAnn Trejo". ASCB. 2017-10-19. Retrieved 2019-02-15.
  30. ↑ https://today.ucsd.edu/story/uc-san-diego-secures-several-top-spots-in-latest-national-rankings-for-nih-funding
  31. ↑ https://crosstalk.cell.com/blog/100-inspiring-hispanic-latinx-scientists-in-america
  32. ↑ Spiro, Mary (2020-09-24). "ASCB Names 18 Members as Its 2020 Fellows Cohort". ASCB. Retrieved 2021-10-19.[dead link]
  33. ↑ "National Academy of Medicine Elects 100 New Members". National Academy of Medicine. 2021-10-18. Retrieved 2021-10-19.
  34. ↑ "2 UCSD scientists elected to National Academy of Medicine". San Diego Union-Tribune. 2021-10-19. Retrieved 2021-10-19.
  35. ↑ https://www.bps.ac.uk/news/article/2024-fellows-and-honorary-fellows-announced/
  36. ↑ https://today.uconn.edu/2025/05/school-of-pharmacy-2025-commencement-speakers/
  37. ↑ https://www.universityofcalifornia.edu/news/50-uc-researchers-elected-american-association-advancement-science
  38. ↑ https://today.ucsd.edu/story/eight-uc-san-diego-researchers-elected-2025-aaas-fellows
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