In enzymology, isopropanol dehydrogenase (NADP+) (EC 1.1.1.80) is an enzyme that catalyzes the chemical reaction
| isopropanol dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.80 | ||||||||
| CAS no. | 37250-18-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The two substrates of this enzyme are isopropanol and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are acetone, reduced NADPH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is propan-2-ol:NADP+ oxidoreductase. This enzyme participates in propanoate metabolism.
References
edit- ↑ Enzyme 1.1.1.80 at KEGG Pathway Database.
- ↑ Hoshino K (1960). "Organism producing isopropanol from acetone. V. Enzymological [studies] on the oxidation-reduction of Lactobacillus brevis var. hofuensis". Nippon Nogeikagaku Kaishi (in Japanese). 34: 608–615. doi:10.1271/nogeikagaku1924.34.7_608.
- ↑ Hoshino K, Udagawa K (1960). "Organism producing isopropanol from acetone. VI. Isopropanol dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var. hofuensis". Nippon Nogeikagaku Kaishi (in Japanese). 34: 616–619. doi:10.1271/nogeikagaku1924.34.7_616.
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