This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[5] It also is a major factor in developing Long COVID as such, increasing the chances of developing the little-understood syndrome 1.6 fold, a finding which has major implications for COVID-19 pandemic research.[6][7]
Katoh M, Katoh M (2005). "Human FOX gene family (Review)". International Journal of Oncology. 25 (5): 1495–1500. doi:10.3892/ijo.25.5.1495. PMID15492844.
Teufel A, Wong EA, Mukhopadhyay M, Malik N, Westphal H (June 2003). "FoxP4, a novel forkhead transcription factor". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1627 (2–3): 147–152. doi:10.1016/S0167-4781(03)00074-5. PMID12818433.
