David Isserman (born March 31, 1983) is an American entrepreneur and conservationist living in Lisbon, Portugal. He is the founder of Isserman Ventures, a firm that invests in and provides operational management to direct-to-consumer e-commerce companies.[1][2][3] From 2020 to 2026, he served on the board of directors of The Explorers Club.[4][5]
Isserman co-founded RareShare, an online platform for rare disease communities, in 2008,[6][7] and founded Venin Royale, a skincare company in Boulder, Colorado, in 2013.[8] Through Pangea Trust, a UK registered charity, he has supported rewilding projects in Portugal's Alentejo region, including the reintroduction of endangered Sorraia horses.[5] In 2023, Duarte Pio, Duke of Braganza made him a Knight of the Order of Saint Michael of the Wing.[4][3]
Early life and education
editIsserman grew up in Clayton, Missouri, and graduated from Clayton High School in 2001.[4] He began building websites for small businesses in middle school and had about 75 clients by high school.[9] At age 14, he approached A.G. Edwards to offer technology consulting services; Alfred Goldman, a corporate vice president at the firm's brokerage subsidiary, later nominated him for the St. Louis Business Journal's 30 Under 30 list, to which he was named in 2006.[9] He earned a Bachelor of Science from Indiana University[4] and an MBA from Columbia Business School.[7][4]
Career
editEarly ventures
editWhile at Indiana University, Isserman founded Isserman Consulting LLC, a communications and web strategy firm in Clayton.[9] In 2006, television host Richard Wiese hired the firm to build his web presence, including a site for Wiese's nationally syndicated show Exploration with Richard Wiese.[10]
RareShare
editIn 2008, while attending Columbia Business School, Isserman co-founded RareShare with Eric Steele.[7][6] The platform connected people affected by rare diseases with one another and with medical professionals.[11] RareShare won the social venture category at the 2008 Pace Pitch Contest hosted by Pace University's Lubin School of Business.[12] In December 2008, TechCrunch described the platform as covering more than 200 rare diseases and partnering with the National Institutes of Health and the Canadian Organization for Rare Disorders.[6] The Washington Post covered the platform in February 2009,[11] and the Toronto Star reported that it hosted discussion groups for hundreds of conditions.[13] RareShare grew to more than 850 communities before Isserman exited in 2014.[4] The platform has been cited in the academic literature on rare-disease drug discovery.[14]
Venin Royale
editIn 2013, Isserman founded Venin Royale, a skincare company in Boulder, Colorado, that used king cobra venom peptides in its products.[8][15] The products were developed with neuroscientist Paul Reid.[8] The line was sold through physician offices, medical spas, and specialty retailers.[8]
Touchstone Essentials
editIsserman Ventures
editIsserman is the founder of Isserman Ventures, which invests in and provides operational management to direct-to-consumer e-commerce companies.[3]
Exploration and conservation
editThe Explorers Club
editIsserman is a graduate of the National Outdoor Leadership School.[9] He joined The Explorers Club in 2002 as a life member.[16][3][4] From March 2020 to April 2026, he served on the club's board of directors.[4][3][5] He chaired the club's annual dinner (ECAD) and co-chaired its Conservation and Sustainability Committee.[4] The club's Global Exploration Summit (GLEX), held in the Azores, was described by Radio France Internationale as the largest gathering of explorers on the planet.[17] In 2025, Isserman contributed to the development of the club's membership app.[16]
In 2024, the Explorers Club awarded Flag No. 179 to the Pangea Trust's rewilding program in Portugal's Alentejo region, where Isserman supported the reintroduction of endangered Sorraia horses.[5][18]

He returned the flag at the 2025 ECAD ceremony.[19]
In 2025, Isserman led the PaleoDiscovery Team on the Dino Dawn Expedition, an Explorers Club flag-bearing paleontological dig in Portugal's Algarve region led by paleontologist Ricardo Araújo.[20][18]
Pangea Trust
editCivic engagement
editIsserman is an advisory trustee of the Academy of Science of St. Louis.[4][22]
Honors
editIn 2023, Duarte Pio, Duke of Braganza, made Isserman a Knight of the Order of Saint Michael of the Wing, a dynastic order of the non-reigning House of Braganza.[4][3]
Personal life
editReferences
edit- 1 2 3 Vetter, Jenny (March 2024). "Touchstone Essentials: Ahead of the Curve". Direct Selling News. Retrieved May 2, 2026.
- 1 2 3 Martin, Heather (October 2017). "Defining Distributors versus Customers". Direct Selling News. Retrieved May 2, 2026.
- 1 2 3 4 5 6 7 8 9 Duraes, Sara J. (March 30, 2024). "Portugal: The new place to be for innovators". The Portugal News. Retrieved May 2, 2026.
- 1 2 3 4 5 6 7 8 9 10 11 12 "Talk of the Towns: Notable Neighbors". Town and Style. November 1, 2023. Retrieved May 2, 2026.
- 1 2 3 4 5 Brookes, Cristina da Costa (November 26, 2024). "Endangered Sorraia horses reintroduced to Alentejo in landmark rewilding effort". The Portugal News. Retrieved May 2, 2026.
- 1 2 3 Kincaid, Jason (December 23, 2008). "RareShare: A Community For People With Rare Medical Problems". TechCrunch. Retrieved May 2, 2026.
- 1 2 3 Wilcox, Joe (October 2, 2008). "RareShare social network builds an uncommon community". BetaNews. Retrieved May 2, 2026.
- 1 2 3 4 Heckel, Aimee (July 31, 2015). "Cobra venom can erase wrinkles? Who knew?". Boulder Daily Camera. Retrieved May 2, 2026.
- 1 2 3 4 McDonald, Michele (July 16, 2006). "David Isserman, 23". St. Louis Business Journal. Retrieved May 2, 2026.
- ↑ "Isserman wins contract from TV host". St. Louis Business Journal. September 18, 2006. Retrieved May 2, 2026.
- 1 2 Bhanoo, Sindya N. (February 10, 2009). "Sharing the Pain". The Washington Post. Retrieved May 2, 2026.
- ↑ "Fifth Annual Pace Pitch Contest". Pace University Lubin School of Business. Retrieved May 2, 2026.
- ↑ "For people with rare ailments, a way to connect". Toronto Star. July 3, 2008. Retrieved May 2, 2026.
- ↑ Litterman, Nadia K.; Rhee, Michele; Swinney, David C.; Ekins, Sean (October 31, 2014). "Collaboration for rare disease drug discovery research". F1000Research. 3: 261. doi:10.12688/f1000research.5564.1. PMC 4314660. PMID 25685324.
- ↑ Weinderman, Coris (September 5, 2013). "Would you put King Cobra venom on your face to reduce wrinkles?". St. Louis Business Journal. Retrieved May 2, 2026.
- 1 2 "The Explorers Club Mobile App to launch November 12, 2025". The Explorers Club. November 10, 2025. Retrieved May 2, 2026.
- ↑ Quaresma, Luciana (June 14, 2023). "Amazonia e o tema central da maior convencao de exploradores do planeta". Radio France Internationale. Retrieved May 2, 2026.
- 1 2 "Flag Expeditions: Field Projects, 2024 and Beyond" (PDF). The Explorers Log. 56 (4). The Explorers Club: 14–17. Fall 2024. Retrieved May 2, 2026.
- ↑ "ECAD Sunday". The Explorers Club. 2025. Retrieved May 2, 2026.
- ↑ "The Team". Dino Dawn Expedition. Retrieved May 2, 2026.
- 1 2 "Team". Pangea Trust. Retrieved May 2, 2026.
- ↑ "Board of Trustees". Academy of Science of St. Louis. Retrieved May 2, 2026.
- ↑ "Gem wins love and adventure for Anna and David". St. Louis Post-Dispatch. August 13, 2015. Retrieved May 2, 2026.
- ↑ "Conservation Forum hailed as a great success by all". Mirpuri Foundation. July 5, 2024. Retrieved May 2, 2026.