Chitin deacetylase

In enzymology, a chitin deacetylase (EC 3.5.1.41) is an enzyme that catalyzes the chemical reaction

chitin deacetylase
Identifiers
EC no.	3.5.1.41
CAS no.	56379-60-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

chitin + H₂O $\rightleftharpoons$ chitosan + acetate

Thus, the two substrates of this enzyme are chitin and H₂O, whereas its two products are chitosan and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chitin amidohydrolase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2IW0.

References

• Araki Y, Ito E (1974). "A pathway of chitosan formation in Mucor rouxii: enzymatic deacetylation of chitin". Biochem. Biophys. Res. Commun. 56 (3): 669–75. Bibcode:1974BBRC...56..669A. doi:10.1016/0006-291X(74)90657-3. PMID 4826874.