α-Isocomene synthase (EC 4.2.3.136, MrTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (–)-α-isocomene-forming).[1] This enzyme catalyses the following chemical reaction
| α-isocomene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.136 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate (–)-α-isocomene + diphosphate
This enzyme is isolated from the roots of the plant Matricaria chamomilla var. recutita (chamomile).
References
edit- ↑ Irmisch S, Krause ST, Kunert G, Gershenzon J, Degenhardt J, Köllner TG (June 2012). "The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils". BMC Plant Biology. 12 (1) 84. Bibcode:2012BMCPB..12...84I. doi:10.1186/1471-2229-12-84. PMC 3423072. PMID 22682202.
External links
edit- Alpha-isocomene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
