Alexandra F. Freeman is an American physician-scientist specializing in pediatric infectious diseases and primary immunodeficiencies. She is a senior clinician at the National Institute of Allergy and Infectious Diseases (NIAID), where her research focuses on hyperimmunoglobulin E syndromes and immune disorders.
Alexandria F. Freeman | |
|---|---|
 | |
| Alma mater | Carleton College Georgetown University |
| Scientific career | |
| Fields | Pediatric infectious diseases, primary immunodeficiencies |
| Institutions | Georgetown University National Institutes of Health |
Education
editFreeman earned a B.A. in biology from Carleton College in 1992. She received a M.D. degree from Georgetown University School of Medicine in 1997.[1] Following medical school, she completed a pediatrics residency at Yale New Haven Children's Hospital from 1997 to 2000.[1] She then pursued a pediatric infectious disease fellowship at Children's Memorial Hospital from 2000 to 2004.[1]
Career
editFreeman began her career as a medical officer in the HIV/AIDS malignancy branch at the National Cancer Institute (NCI) from 2004 to 2005.[1] She then joined the laboratory of clinical infectious diseases at the National Institute of Allergy and Infectious Diseases (NIAID) as a staff clinician from 2005 to 2008.[1]
From 2006 to 2008, she held an assistant professor position in the department of pediatrics at Georgetown University Hospital, where she was affiliated with the pediatric infectious diseases program.[1] In 2008, she transitioned to a role as Physician II at SAIC-Frederick, working in the clinical monitoring research branch in support of the NIAID laboratory of clinical infectious diseases at the Frederick National Laboratory for Cancer Research.[1] She held this position until 2009, when she returned to NIAID at first as a staff clinician and later senior clinician.[1]
Freeman's early research focused on pediatric HIV.[2] In 2005, she shifted her focus to primary immunodeficiencies, including hyperimmunoglobulin E syndromes.[2] At NIAID, Freeman works in the primary immune deficiency clinic, where she is involved in the diagnosis, evaluation, and management of patients with primary immunodeficiencies, particularly hyper-IgE syndromes.[3] She has studied patients with STAT3-mutated Hyper-IgE syndrome (STAT3 DN; Job's syndrome), which involves eczema, recurrent infections, and connective tissue abnormalities.[3]
Her research has examined the role of STAT3 in immunity, infection susceptibility, and tissue remodeling.[3] She has also investigated treatment options, including hematopoietic stem cell transplantation and gene editing.[3] Freeman is the director of the primary immunodeficiency clinic at NIAID, where she trains allergy and immunology fellows in diagnosing and managing primary immunodeficiencies.[3]
References
edit- 1 2 3 4 5 6 7 8 Freedman, Alexandria (2013). "Curriculum vitae: Alexandria Freedman". demystifyingmedicine.od.nih.gov. Retrieved 2025-03-29 – via Yumpu.
- 1 2 "Episode #84: Dr. Alexandra Freeman". Made Visible Stories. Retrieved 2025-03-29.
- 1 2 3 4 5 "Faculty Profile: Alexandra F. Freeman, M.D." NIH Intramural Research Program. Retrieved 2025-03-29.
This article incorporates text from this source, which is in the public domain.