5-MeO-PiPT

5-MeO-PiPT
Clinical data
Other names	5-Methoxy-N-propyl-N-isopropyltryptamine; Poxy
Drug class	Non-selective serotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
Identifiers
	IUPAC name N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-(propan-2-yl)propan-1-amine;
CAS Number	2945111-53-3 ;
PubChem CID	166468735;
Chemical and physical data
Formula	C17H26N2O
Molar mass	274.408 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N(CCC)CCc1c[NH]c2ccc(cc21)OC;
	InChI InChI=1S/C17H26N2O/c1-5-9-19(13(2)3)10-8-14-12-18-17-7-6-15(20-4)11-16(14)17/h6-7,11-13,18H,5,8-10H2,1-4H3; Key:KLRSMSBDLVDLKK-UHFFFAOYSA-N;

5-MeO-PiPT, also known as 5-methoxy-N-propyl-N-isopropyltryptamine or by its nickname Poxy, is a substituted tryptamine derivative which is claimed to have psychedelic effects.^[1]^[2] It has been sold as a designer drug, first being identified in 2021 in British Columbia, Canada.^[3]

Use and effects

5-MeO-PiPT was not included nor mentioned in Alexander Shulgin's book TiHKAL (Tryptamines I Have Known and Loved).^[4]

5-MeO-PiPT acts as a serotonin 5-HT_1A and 5-HT_2A receptor agonist,^[1] with an EC₅₀Tooltip half-maximal effective concentration of 13.8 nM and an efficacy of 89%.^[2]