2C-AL

2C-AL, also known as 4-allyl-2,5-dimethoxyphenethylamine, is a drug from the substituted phenethylamine family which acts as an agonist of the 5-HT_2A receptor, with an EC₅₀Tooltip half-maximal effective concentration of 2.15 nM at 5-HT_2A vs. 77.71 nM at 5-HT_2B, and produces a head-twitch response in animal studies. It was first discussed as a hypothetical compound in Daniel Trachsel's 2013 review of the field after his successful synthesis of the related compounds 2C-V and 2C-YN, and finally synthesised by a team at Gilgamesh Pharmaceuticals in 2020 using a different synthetic route from that employed by Trachsel. It is a controlled substance in Canada under phenethylamine blanket-ban language.

2C-AL

Clinical data
Other names	4-Allyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-allylphenethylamine
Routes of administration	Unknown
Drug class	Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
Pharmacokinetic data
Duration of action	Unknown
Identifiers
IUPAC name 2-(2,5-dimethoxy-4-prop-2-enylphenyl)ethanamine
CAS Number	2756686-02-7
PubChem CID	162430125
ChemSpider	129432010
UNII	DY8B23CT6A
Chemical and physical data
Formula	C13H19NO2
Molar mass	221.300 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1CCN)OC)CC=C
InChI InChI=1S/C13H19NO2/c1-4-5-10-8-13(16-3)11(6-7-14)9-12(10)15-2/h4,8-9H,1,5-7,14H2,2-3H3 Key:QNVPDGCJKPQARD-UHFFFAOYSA-N

See also

• 2C (psychedelics)
• 2C-CP
• 2C-IP
• 2C-P
• 2C-T-16
• 2C-T-TFM
• Allylescaline
• 3C-AL

External links

• 2C-AL - Isomer Design