2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase (EC 2.1.1.241, BX7 (gene), OMT BX7) is an enzyme with systematic name S-adenosyl-L-methionine:(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl β-D-glucopyranoside 7-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction
| 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.241 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- S-adenosyl-L-methionine + (2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl β-D-glucopyranoside S-adenosyl-L-homocysteine + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl β-D-glucopyranoside
The enzyme is involved in the biosynthesis of the protective and allelopathic glucoside of the benzoxazinoid, DIMBOA, e.g. from the family Poaceae (grasses).
References
edit- ↑ Jonczyk R, Schmidt H, Osterrieder A, Fiesselmann A, Schullehner K, Haslbeck M, Sicker D, Hofmann D, Yalpani N, Simmons C, Frey M, Gierl A (March 2008). "Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7". Plant Physiology. 146 (3): 1053–63. doi:10.1104/pp.107.111237. PMC 2259038. PMID 18192444.
External links
edit- 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside+7-O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
