The 1988 Campeón de Campeones was the 35th edition of the Campeón de Campeones, an annual footballsuper cup match.[a] The competition had not been played since 1976, marking this edition as its revival after a 12-year hiatus. Unlike most editions, this edition was played over two-legs, making it the second instance in the competition's history to use this format, the first being in 1968. The match-up featured América, the winners of the 1987–88 Mexican Primera División, and Puebla, the winners of the 1987–88 Copa México. The first-leg was played on 7 July 1988 at Estadio Cuauhtémoc, Puebla and the second-leg on 10 July 1988 at Estadio Azteca, Mexico DF.
In the first-leg, Puebla defeated América 2–1, but in the second-leg América responded with a 2–0 victory, winning the tie 3–2 on aggregate and claiming their third Campeón de Campeones title.