This article needs to be updated. (June 2023) |
Huxley's layer is the middle layer of the inner root sheath of the hair follicle, situated between Henle's layer (outermost) and the IRS cuticle (innermost). It consists of two to four cells in thickness and contains numerous trichohyalin granules, which are essential for keratinization and provide mechanical strength by cross-linking keratin filaments.[1]
| Huxley's layer | |
|---|---|
Transverse section of hair follicle | |
| Identifiers | |
| FMA | 70939 |
| Anatomical terminology | |
Huxley's layer keratinizes after both the IRS cuticle and the hair cuticle. The three layers of the inner root sheath are distinct just above the dermal papilla but become indistinguishable at higher levels, where they function as a single unit that molds and protects the growing hair shaft.[2]
Naming
editThe layer is named after English biologist Thomas Henry Huxley.[3]
See also
editReferences
edit- ↑ "Hair Anatomy". Medscape. Retrieved 2026-05-25.
- ↑ Histology, Hair and Follicle. StatPearls, NCBI. 2023.
- ↑ Steffen, C (February 2002). "The man behind the eponym: Thomas Henry Huxley: Huxley's layer of the inner root sheath". The American Journal of Dermatopathology. 24 (1): 82–4. doi:10.1097/00000372-200202000-00017. PMID 11803289.