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Summary
| Description |
English: MER41 endogenous retroviral elements regulate the response to viral infection.
The vaccinia virus triggers IFN-γ to stimulate the transcription factor STAT1. Binding of STAT1 to MER41 results in the upregulation of AIM2, which detects the cytosolic DNA genome of vaccinia and initiates an inflammatory response. |
| Date | |
| Source | https://www.sciencedirect.com/science/article/pii/S0960982216303177 |
| Author | Aris Katzourakis |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 05:12, 8 June 2026 | | 2,237 × 1,828 (490 KB) | Nahleghini | Uploaded a work by Aris Katzourakis from https://www.sciencedirect.com/science/article/pii/S0960982216303177 with UploadWizard |
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