File:Apalutamide synthesis.svg

Original file (SVG file, nominally 512 × 180 pixels, file size: 79 KB)

Summary

Description
English: Flick, A. C., Leverett, C. A., Ding, H. X., McInturff, E., Fink, S. J., Helal, C. J., DeForest, J. C., Morse, P. D., Mahapatra, S., O’Donnell, C. J. (8 October 2020). "Synthetic Approaches to New Drugs Approved during 2018". Journal of Medicinal Chemistry. 63 (19): 10652–10704. doi:10.1021/acs.jmedchem.0c00345.

Hughes, D. L. (20 March 2020). "Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide". Organic Process Research & Development. 24 (3): 347–362. doi:10.1021/acs.oprd.0c00005.

Wang, H., Li, L., Yang, F., Li, D., Wu, S., Yan, W., Sun, G., Tan, J., Li, Y., Yang, H., Wang, Z. (October 2025). "Process development and optimization of apalutamide synthesis aided by the Design of Experiments (DoE)". Tetrahedron. 184: 134725. doi:10.1016/j.tet.2025.134725.
Date
Source Own work
Author Yogi Yolk

Licensing

I, the copyright holder of this work, hereby publish it under the following license:
Creative Commons CC-Zero This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication.
The person who associated a work with this deed has dedicated the work to the public domain by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.

Captions

Apalutamide synthesis

Items portrayed in this file

depicts

24 February 2026

80,386 byte

image/svg+xml

698d29c418612ad766e9f5276ef624fc58ae9bb8

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current14:59, 24 February 2026Thumbnail for version as of 14:59, 24 February 2026512 × 180 (79 KB)Yogi Yolktweaked
12:01, 24 February 2026Thumbnail for version as of 12:01, 24 February 2026512 × 180 (77 KB)Yogi YolkUploaded own work with UploadWizard

The following page uses this file:

Metadata