An aromatic-amino-acid-glyoxylate transaminase (EC 2.6.1.60) is an enzyme that catalyzes the chemical reaction
| Aromatic-amino-acid-glyoxylate transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.60 | ||||||||
| CAS no. | 67185-76-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- an aromatic amino acid + glyoxylic acid an aromatic oxo acid + glycine
Thus, the two substrates of this enzyme are aromatic amino acid and glyoxylic acid. Its products are the corresponding α-keto acid and glycine.
For example, the enzyme characterised from liver interconverts phenylalanine and phenylpyruvic acid:[1]
This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is aromatic-amino-acid:glyoxylate aminotransferase.[2]
