Metaphedrine

Metaphedrine
Clinical data
Other names	3-Methyl-N-methylamphetamine; 3-MMA; 3MMA; 3-Me-MA; Metaphedrine
Legal status
Legal status	US: Schedule I (isomer of Etilamfetamime);
Identifiers
	IUPAC name N-methyl-1-(3-methylphenyl)propan-2-amine;
CAS Number	861007-68-3;
PubChem CID	24257262;
ChemSpider	23900070;
UNII	ANT66P7LWF;
CompTox Dashboard (EPA)	DTXSID501343157 ;
Chemical and physical data
Formula	C11H17N
Molar mass	163.264 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC(=CC=C1)CC(C)NC;
	InChI InChI=1S/C11H17N/c1-9-5-4-6-11(7-9)8-10(2)12-3/h4-7,10,12H,8H2,1-3H3; Key:CXVNKBVJDKMLOH-UHFFFAOYSA-N;

Metaphedrine,^[1] or 3-methylmethamphetamine (3-MMA), is a methamphetamine derivative which has been sold as a designer drug, with the substance first encountered online in 2020 and reported in Sweden in 2021.^[2]^[3] It is a potent monoamine reuptake inhibitor^[4] and is thought to have psychostimulant effects.^[3] The drug was not active as a serotonin 5-HT_2A receptor agonist.^[4]

References

↑ "Metaphedrine - FDA Global Substance Registration System". Food and Drug Administration. March 4, 2026. Archived from the original on April 19, 2026. Retrieved 2026-04-19.
↑ European Monitoring Centre for Drugs and Drug Addiction. (June 2022). New psychoactive substances: 25 years of early warning and response in Europe. An update from the EU Early Warning System (PDF). European Monitoring Centre for Drugs and Drug Addiction. doi:10.2810/882318 (inactive 12 July 2025). ISBN 978-92-9497-737-3.{{cite book}}: CS1 maint: DOI inactive as of July 2025 (link)
1 2 "3-MMA (3-Метилметамфетамин)". АИПСИН (in Russian). Retrieved 1 January 2026.
1 2 Stalberga D, Kronstrand R, Schranz B, van Zijl N, Karlman S, Aref S, et al. (2025). "Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor". Authorea. doi:10.22541/au.176253891.19158813/v1.

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