The 2025–26 CAF Confederation Cup group stage began on 22 November 2025 and ended on 15 February 2026. 16 teams competed in the group stage to decide the eight places in the knockout stage of the 2025–26 CAF Confederation Cup.
The teams were seeded by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown next to every team). Each group contained one team from each of Pot 1, Pot 2, and Pot 3, and each team was allocated to the positions in their group according to their pot.
In the group stage, each group was played on a home-and-away round-robin basis. The winners and runners-up of each group advanced to the quarter-finals of the knockout stage.
The teams were ranked according to points (3 points for a win, 1 point for a draw, 0 points for a loss). If tied on points, tiebreakers were applied in the following order (Regulations III. 20 & 21):
Goals scored in head-to-head matches among tied teams;
Away goals scored in head-to-head matches among tied teams;
If more than two teams were tied, and after applying all head-to-head criteria above, a subset of teams was still tied, all head-to-head criteria above were reapplied exclusively to this subset of teams;